Objective:To evaluate the applied value of the neuronavigation in intracranial cavernous angioma(CA)microsurgery. Methods: Sixty-seven cases of intracranial CA were resected under neuronavigation-assisted microsurgery, and the operative effect was analyzed. Results: Of all cases, the focuses of infection were accurately located and the focuses were resected successfully. No death case was observed in the procedure. CT or magnetic resonance imaging showed that the focuses of infection were not reliquus after the surgery. The patients’ clinical symptoms were improved after the surgery. Muscle weakness(11 cases)and dysphonia(2 cases) patients were cure through neurological rehabilitative treatment. Neurological functions damage was not observed in the rest cases. Conclusion: Neuronavigation -assisted microsurgery can accurately locate in resecting CA. It can dynamically trace, and minimally invade in resecting focuses of infection,and it can protect the nerve function and reduce the incidence of surgical complications.